Lottini Michele, Neri Alessandro, Vuolo Giuseppe, Testa Michele, Pergola Loreta, Cintorino Marcella, Guarnieri Alfredo
Institute of Surgical Sciences, University of Siena, Italy.
Tumori. 2002 Sep-Oct;88(5):427-9. doi: 10.1177/030089160208800517.
Metastatic involvement of the upper gastrointestinal tract from breast cancer has been reported in autopsy series as occurring in more than 15% of patients, usually associated with extensive systemic spread; clinical manifestations from such metastases have been described in less than 1% of cases. Lobular infiltrating carcinoma seems to have a different metastatic pattern than the ductal type, with an apparent predilection for the gastrointestinal tract. Metastatic presentation as an isolated intestinal obstruction without other signs of metastatic spread is extremely rare. We present a case of isolated duodenal metastasis from breast cancer, associated with intestinal obstruction, as the first sign of metastatic spread.
尸检系列报告显示，乳腺癌转移至上消化道的情况在超过15%的患者中出现，通常与广泛的全身扩散相关；而此类转移的临床表现仅在不到1%的病例中有所描述。小叶浸润癌似乎具有与导管型不同的转移模式，明显更易转移至胃肠道。以孤立性肠梗阻作为转移表现且无其他转移扩散迹象的情况极为罕见。我们报告一例乳腺癌孤立性十二指肠转移病例，该病例以肠梗阻为转移扩散的首发症状。
