Fewings P E, Bhattacharyya D, Crooks D, Morris K
Department of Neurosurgery, Hull Royal Infirmary, Hull, UK.
Clin Neuropathol. 2002 Nov-Dec;21(6):243-7.
Primary central nervous system lymphomas and anaplastic oligodendrogliomas are not uncommon; however, no association between the 2 has been documented to date. We describe a unique case, whereby a patient presenting with seizures and slight impairment of higher functions, underwent frontal lobectomy for a mass lesion. The histology revealed dual pathology of anaplastic oligodendroglioma and B cell non-Hodgkin lymphoma. Postoperatively, the patient received whole brain radiotherapy. The patient remained well after 18 months of follow-up with no radiological progression of a known tumor residuum.
原发性中枢神经系统淋巴瘤和间变性少突胶质细胞瘤并不罕见；然而，迄今为止尚未有两者之间关联的文献记载。我们描述了一个独特的病例，一名出现癫痫发作和高级功能轻度受损的患者因肿块病变接受了额叶切除术。组织学检查显示为间变性少突胶质细胞瘤和B细胞非霍奇金淋巴瘤的双重病理。术后，患者接受了全脑放疗。随访18个月后患者情况良好，已知的肿瘤残留无影像学进展。
