Rosch Deborah S, Sajatovic Martha, Sivec Harry
Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Int J Psychiatry Med. 2002;32(3):295-303. doi: 10.2190/VRV7-7H3T-F5WF-A4B7.
False pregnancy or delusional pregnancy, is the condition of believing one is pregnant despite factual evidence to the contrary. This is the first study to utilize a standardized mental disorder assessment tool, The Brief Psychiatric Rating Scale (BPRS) to evaluate a group of women with delusional pregnancy compared to a group of controls.
Eleven-women with delusional pregnancy (DP) were compared to a control group matched for age, race and DSM-IV psychiatric diagnosis. All patients were receiving care in a state psychiatric hospital setting.
Compared to matched controls, women with DP had significantly higher levels of hostility (p < .05), higher rates of prescribed polypharmacy (p < .05) and a trend toward higher antipsychotic medication dosages (t = 1.48, df = 20, p = .08). These findings may be suggestive of greater resistance to treatment in women with DP.
Biologic and psychotherapeutic treatment interventions for women with DP may need to address factors of hostility and treatment resistance. Preliminary treatment issues include selection of specific categories of psychotropic agents, as well as psychotherapies that are cognitive and lead to modification of belief paradigm.
假孕或妄想性妊娠是指尽管有相反的事实证据，但仍坚信自己怀孕的情况。这是第一项利用标准化精神障碍评估工具——简明精神病评定量表（BPRS）对一组妄想性妊娠女性与一组对照组进行评估的研究。
将11名妄想性妊娠（DP）女性与一个在年龄、种族和DSM-IV精神疾病诊断方面相匹配的对照组进行比较。所有患者均在一家州立精神病医院接受治疗。
与匹配的对照组相比，DP女性的敌意水平显著更高（p < 0.05），联合用药的处方率更高（p < 0.05），并且抗精神病药物剂量有升高的趋势（t = 1.48，自由度 = 20，p = 0.08）。这些发现可能表明DP女性对治疗的抵抗性更强。
针对DP女性的生物和心理治疗干预可能需要解决敌意和治疗抵抗等因素。初步治疗问题包括选择特定类别的精神药物，以及采用认知性且能导致信念范式改变的心理治疗方法。
