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芒果茎皮和椭圆叶蒲葵根对气管平滑肌的体外作用。

The effect of Mangifera indica stem bark and Pluchea ovalis roots on tracheal smooth muscle in vitro.

作者信息

Agbonon Amégnona, Eklu-Gadegbeku Kwashie, Aklikokou Kodjo, Essien Komlan, Akpagana Koffi, Gbeassor Messanvi

机构信息

Département de Physiologie/Pharmacologie Faculté des Sciences, Université de Lomé BP, 1515 Lomé, Togo.

出版信息

Fitoterapia. 2002 Dec;73(7-8):619-22. doi: 10.1016/s0367-326x(02)00230-7.

DOI:10.1016/s0367-326x(02)00230-7
PMID:12490220
Abstract

Aqueous extract of the stem bark of Mangifera indica and ethanolic extract of the roots of Pluchea ovalis has been studied on rat tracheal smooth muscle in vitro. The extract of M. indica at 1, 2 and 4 mg/ml and that of P. ovalis at 0.25, 0.5 and 1 mg/ml relaxed, dose-dependently, the rat tracheal smooth muscle strip previously contracted by acetylcholine at 0.055 mmol/l.

摘要

已对芒果茎皮水提取物和椭圆叶蒲葵根乙醇提取物对大鼠气管平滑肌进行体外研究。芒果提取物浓度为1、2和4mg/ml,椭圆叶蒲葵提取物浓度为0.25、0.5和1mg/ml时,可剂量依赖性地舒张先前由0.055mmol/l乙酰胆碱收缩的大鼠气管平滑肌条。

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