Isler H
J Cell Sci. 1976 Jan;20(1):135-47. doi: 10.1242/jcs.20.1.135.
This paper describes the fine structure of epithelial vesicles as observed in the thymus of the chicken. Three types of vesicles are found. The largest is made up of a stratified columnar epithelium containing lymphoid cells. The lumen contains a fairly light material and cell debris. The lumen-bordering cells are columnar and their microvilli are sometimes developed to such an extent as to appear as a brush border. The wall of the vesicles contains lymphocytes and granular cells with dense granules 100-500 nm in diameter. Smaller vesicles are found which contain no lymphoid cells. They are made of a simple or stratified epithelium containing typical mucous cells, and columnar cells similar to the bordering cells of the large vesicles. The third type is an intracytoplasmic vesicle in epithelial reticular cells, which differs from usual vacuoles by the presence of microvilli and its often unusually large size. The morphology of the first 2 types of vesicles indicates a secretory capability, the function of which is unknown. Data from the literature suggest that the third type produces the factor(s) conferring cellular immunological competence.
本文描述了在鸡胸腺中观察到的上皮小泡的精细结构。发现了三种类型的小泡。最大的小泡由含有淋巴细胞的复层柱状上皮组成。腔内含有相当浅色的物质和细胞碎片。与腔相邻的细胞呈柱状，其微绒毛有时发育到呈现刷状缘的程度。小泡壁含有淋巴细胞和直径为100 - 500纳米的致密颗粒的颗粒细胞。还发现了较小的不含淋巴细胞的小泡。它们由含有典型粘液细胞的单层或复层上皮以及与大泡相邻细胞相似的柱状细胞组成。第三种类型是上皮网状细胞内的胞质小泡，它与通常的液泡不同之处在于有微绒毛且其大小常常异常大。前两种类型小泡的形态表明它们具有分泌能力，但其功能尚不清楚。文献数据表明第三种类型产生赋予细胞免疫能力的因子。
