模拟多形性腺瘤的肺乳头状肺细胞瘤。

Papillary pneumocytoma of the lung simulating a pleomorphic adenoma.

作者信息

Baldi Alfonso, Santini Mario, Vicidomini Giovanni, Ambrosino Francesco, Vincenzi Bruno, Costanzo Rosaria, Di Leo Carmen, Esposito Vincenzo, Groeger Angela M, Baldi Feliciano

机构信息

Department of Biochemistry and Biophysic F. Cedrangolo, Section of Anatomic Pathology, Second University of Naples, Naples, Italy.

出版信息

In Vivo. 2002 Sep-Oct;16(5):387-90.

PMID:12494880

Abstract

A rare case of papillary pneumocytoma of the lung is reported. The immunohistochemical positivities for EMA, cytokeratin and TTF-l strongly support the hypothesis that the neoplastic cells are originated from type 2 pneumocytes. The tumour also presented areas displaying stroma of non-specific mixoid appearance, simulating a benign tumour of the salivary gland type. We propose that these mixoid areas constitute structures of metaplastic origin.

摘要

报告了一例罕见的肺乳头状肺细胞瘤。上皮膜抗原（EMA）、细胞角蛋白和甲状腺转录因子-1（TTF-1）的免疫组化阳性强烈支持肿瘤细胞起源于Ⅱ型肺泡上皮细胞的假说。肿瘤还呈现出具有非特异性黏液样外观间质的区域，类似涎腺型良性肿瘤。我们认为这些黏液样区域构成化生起源的结构。