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低收入国家的产后抑郁症与婴儿生长发育:来自印度果阿的一项队列研究

Postnatal depression and infant growth and development in low income countries: a cohort study from Goa, India.

作者信息

Patel V, DeSouza N, Rodrigues M

机构信息

London School of Hygiene and Tropical Medicine, London, UK.

出版信息

Arch Dis Child. 2003 Jan;88(1):34-7. doi: 10.1136/adc.88.1.34.

Abstract

BACKGROUND

Postnatal depression is a recognised cause of delayed cognitive development in infants in developed countries. Being underweight is common in South Asia.

AIMS

To determine whether postnatal depression contributes to poor growth and development outcomes in Goa, India.

METHODS

Cohort study for growth outcomes with nested case-control study for developmental outcomes. A total of 171 babies were weighed and measured at 6-8 weeks following birth. The following measures were used: Edinburgh Postnatal Depression Scale for maternal mood, and sociodemographic and infant health variables. Outcome measures were: weight (<5th centile), length (<5th centile), and Developmental Assessment Scale for Indian Infants scores at six months.

RESULTS

Postnatal depression was a strong, and independent, predictor of low weight and length and was significantly associated with adverse mental development quotient scores.

CONCLUSIONS

This study provides evidence for the first time that postnatal depression, a potentially treatable disorder, is a cause of poor growth and development in South Asia.

摘要

背景

在发达国家,产后抑郁是导致婴儿认知发育迟缓的一个公认原因。体重过轻在南亚很常见。

目的

确定在印度果阿邦,产后抑郁是否会导致生长发育不良。

方法

针对生长结局进行队列研究,针对发育结局进行嵌套病例对照研究。共对171名婴儿在出生后6至8周进行了称重和测量。采用了以下测量方法:用于评估母亲情绪的爱丁堡产后抑郁量表,以及社会人口统计学和婴儿健康变量。结局指标包括:体重(低于第5百分位数)、身长(低于第5百分位数),以及六个月时印度婴儿发育评估量表得分。

结果

产后抑郁是体重和身长偏低的一个强有力的独立预测因素,并且与不良的智力发育商数得分显著相关。

结论

本研究首次提供证据表明,产后抑郁这一潜在可治疗的疾病是南亚地区生长发育不良的一个原因。

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