Esedov E M, Khamidova Kh A, Shakhnazarova Kh A
Ter Arkh. 2002;74(11):50-2.
To examine the levels of aspartate aminotransferase (AsAT) and alaninaminotransferase (AlAT) in homogenates of hepatic biopsies from patients with echinococcosis.
Clinical, biochemical examinations, ultrasonic examination of the liver were made in 49 patients with hydatid echinococcosis of the liver and 5 control patients operated on for extrahepatic pathology. Morphological picture of the liver was examined with light microscopy. AsAT and AlAT activity in hepatic tissue were estimated with 2,4-dinitrophenilhydrazin method.
There were marked cellular and extracellular disorders and significant lowering of transaminases in the pericystic zone of hepatic tissue vs such indices for far from the echynococcal cyst sites of the liver.
In hepatic echinococcosis hepatic tissue undergoes diffuse alteration associated with severe morphofunctional disorders which require adequate preoperative preparation of the patients, in postoperative period adequate intensive therapy is needed.
检测棘球蚴病患者肝脏活检组织匀浆中天冬氨酸转氨酶（AsAT）和丙氨酸转氨酶（AlAT）的水平。
对49例肝包虫病患者和5例因肝外病变接受手术的对照患者进行临床、生化检查及肝脏超声检查。用光镜检查肝脏的形态学表现。采用2,4 - 二硝基苯肼法测定肝组织中AsAT和AlAT活性。
与肝脏远离棘球蚴囊肿部位的指标相比，肝组织包囊周围区存在明显的细胞和细胞外紊乱，转氨酶显著降低。
在肝棘球蚴病中，肝组织发生弥漫性改变，伴有严重的形态功能障碍，这需要患者进行充分的术前准备，术后需要进行充分的强化治疗。
