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A case of solitary fibrous tumor of the parotid gland: review of the literatures.

作者信息

Kumagai Masaki, Suzuki Hideaki, Takahashi Etsu, Matsuura Kazuto, Furukawa Masayuki, Suzuki Hiroyoshi, Tezuka Fumiaki

机构信息

Department of Otolaryngology, Sendai National Hospital, Sendai 983-8520, Japan.

出版信息

Tohoku J Exp Med. 2002 Sep;198(1):41-6. doi: 10.1620/tjem.198.41.

Abstract

We report a rare case of solitary fibrous tumor of the parotid gland. A 47-year-old woman presented with a 3-year-history of left-sided subauricular swelling. Computed tomographic scans and magnetic resonance images revealed a well-defined and dumbbell-shaped mass, measuring about 30 mm in its greatest dimension, in the left parotid gland. Because the tumor occupied both superficial and deep lobes of the gland, she underwent total parotidectomy with preservation of the facial nerve. The microscopic finding showed short-spindle and ovoid cells arranged in a haphazard pattern with interspersed thin collagen fibrils. Immunohistochemically, the tumor cells were strongly positive for CD34, bcl-2 and vimentin, whereas stains for S-100, cytokeratin, smooth muscle actin, collagen type IV and CD117 (KIT) were negative. On the basis of these findings, the tumor was diagnosed as solitary fibrous tumor. Her post-operative course was uneventful, and she is currently free from disease 14 months after surgery. Diagnosis, clinical behavior and treatment of solitary fibrous tumor are reviewed from perusal of the literature.

摘要

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