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中枢神经系统罕见的孤立性纤维瘤:两例报告。

Unusual solitary fibrous tumors in the central nervous system: a report of two cases.

作者信息

Hu Shih-Wen, Tsai Kun-Bow, Yang Sheau-Fang, Lee Kung-Shing, Chai Chee-Yin

机构信息

Department of Pathology, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan.

出版信息

Kaohsiung J Med Sci. 2005 Apr;21(4):179-84. doi: 10.1016/S1607-551X(09)70298-0.

Abstract

Solitary fibrous tumors (SFTs) are uncommon, and most are found in the pleura. Extrapleural SFTs are rare and have been found in the lung, pericardium, mediastinum, soft tissue of any site, and upper respiratory tract. SFTs of the central nervous system (CNS) are very rare. The biologic features are unknown and remain poorly understood from a clinical standpoint. Most neurosurgeons do not believe that SFTs can present as primary CNS neoplasms. Most SFTs are clinically benign and indolent, and recurrences after surgical excision are scarce. Because malignant transformation or metastasis has been reported, all SFTs should be treated as having malignant potential. Long-term follow-up is recommended. We report two cases, so that surgeons may recognize that this is an entity different from other spindle-cell CNS tumors.

摘要

孤立性纤维性肿瘤(SFTs)并不常见,多数发生于胸膜。胸膜外SFTs罕见,可见于肺、心包、纵隔、任何部位的软组织及上呼吸道。中枢神经系统(CNS)的SFTs极为罕见。其生物学特性尚不清楚,从临床角度来看仍了解甚少。多数神经外科医生并不认为SFTs可表现为原发性CNS肿瘤。多数SFTs在临床上呈良性且生长缓慢,手术切除后复发少见。由于已有恶性转化或转移的报道,所有SFTs均应被视为具有恶性潜能。建议进行长期随访。我们报告两例病例,以便外科医生能够认识到这是一种与其他梭形细胞CNS肿瘤不同的实体。

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