Ohki Masafumi, Matsuzaki Masaki, Sugasawa Keiko, Murofushi Toshihisa
Department of Otolaryngology, University of Tokyo, Hongo, Japan.
ORL J Otorhinolaryngol Relat Spec. 2002 Nov-Dec;64(6):424-8. doi: 10.1159/000067566.
We recorded vestibular evoked myogenic potentials (VEMPs) in 12 patients diagnosed as having ipsilateral delayed endolymphatic hydrops (DEH). Seventy-five percent (9/12) of the patients showed decreased or absent VEMPs in the affected ears. Almost all patients had normal VEMPs in the unaffected ears. In addition, in 4 patients, VEMPs were recorded before and 3 h after oral glycerol administration (1.3 g/kg body weight). VEMPs improved after glycerol administration in 2 of the 3 patients whose VEMPs had been abnormal in the affected ears before glycerol administration. None of the 4 patients presented significant changes in VEMPs in the unaffected ears after glycerol administration. Improvement of VEMPs after glycerol administration confirmed the existence of endolymphatic hydrops in patients with ipsilateral DEH. In conclusion, VEMPs are useful to evaluate the function of otolith organs in patients with ipsilateral DEH, and the glycerol test using VEMPs may be useful to detect endolymphatic hydrops in ipsilateral DEH.
我们对12例被诊断为同侧迟发性内淋巴积水（DEH）的患者记录了前庭诱发肌源性电位（VEMP）。75%（9/12）的患者患侧耳VEMP降低或消失。几乎所有患者的健侧耳VEMP均正常。此外，对4例患者在口服甘油（1.3 g/kg体重）前及给药后3小时记录了VEMP。在给药前患侧耳VEMP异常的3例患者中，有2例在甘油给药后VEMP得到改善。4例患者中无一例在甘油给药后健侧耳VEMP出现显著变化。甘油给药后VEMP的改善证实了同侧DEH患者存在内淋巴积水。总之，VEMP有助于评估同侧DEH患者耳石器官的功能，使用VEMP的甘油试验可能有助于检测同侧DEH中的内淋巴积水。
