Divertie M B, Cassan S M, O'Brien P C, Brown A L
Mayo Clin Proc. 1976 Jan;51(1):42-7.
Samples of lung biopsy tissue from nine patients with normal lungs, seven with pulmonary sarcoidosis, nine with diffuse interstitial pulmonary fibrosis, seven with histiocytosis X, and one with asbestosis were analyzed by morphometric techniques applied to electron micrographs, and the results were subjected to rank-sum analysis. Within the limits of the sampling method and the mathematical predictions of others, the general rejection of the constructed hypothesis in this study supports the conclusion that factors other than increase in the arithmetic of harmonic mean thickness of the blood-air barrier are critical to impaired gas transfer in the diseases studied.
对9例正常肺、7例肺结节病、9例弥漫性间质性肺纤维化、7例组织细胞增多症X和1例石棉沉着病患者的肺活检组织样本进行了电子显微镜形态计量学分析，并对结果进行了秩和分析。在抽样方法和其他人的数学预测范围内，本研究对所构建假设的总体否定支持了这样的结论：在所研究的疾病中，除了气血屏障调和平均厚度算术值增加之外的其他因素对气体交换受损至关重要。
