Düwel D, Kirsch R
Z Parasitenkd. 1975;46(1):83-90. doi: 10.1007/BF00383671.
Helminth-free bulls were injected artificially with Ostertagia ostertagi (120 000 L3), Cooperia oncophora (240000 L3), Haemonchus spec. (1 000 L3) and/or Dictyocaulus viviparus (60 L3/kg) orally or intraruminally. The animals were treated with fenbendazole during the prepatent period or after having reached maturity. The effect of 5 mg fenbendazole/kg p.o. on 3-d, 10-d- and adult stages of Ostertagia ostertagi, Haemonchus spec. and Cooperia oncophora ranges between less than 94% and 100%. Particularly noticeable was the effect on 10-d-old Ostertagia ostertagi with less than 94%. 5 mg/kg fenbendazole orally removed nearly 100% of 6-d-, 13-d-, and adult stages of Dictyocaulus viviparus. Fenbendazole may be administered as a drench or as medicated feed. The safety of the compound permits the administration of excessively high doses without clinical signs.
将没有蠕虫的公牛人工经口或瘤胃内注射奥斯特他吉奥斯特他吉（120000 条 L3 幼虫）、牛副蛔虫（240000 条 L3 幼虫）、血矛线虫属（1000 条 L3 幼虫）和/或胎生网尾线虫（60 条 L3 幼虫/千克）。在潜伏期或达到成熟后，用芬苯达唑对动物进行治疗。口服 5 毫克芬苯达唑/千克对奥斯特他吉奥斯特他吉、血矛线虫属和牛副蛔虫的 3 日龄、10 日龄和成虫阶段的驱虫效果在不到 94%至 100%之间。特别值得注意的是对 10 日龄奥斯特他吉奥斯特他吉的效果，其驱虫率不到 94%。口服 5 毫克/千克芬苯达唑可清除近 100%的 6 日龄、13 日龄和成虫阶段的胎生网尾线虫。芬苯达唑可以制成水剂或加药饲料给药。该化合物的安全性允许给予过高剂量而无临床症状。
