Storelli M M, Marcotrigiano G O
Pharmacological-Biologic Department, Chemistry and Biochemistry Section, Medicine Veterinary Faculty, University of Bari, Strada Prov. le per Casamassima km 3, 70010 Valenzano, Bari, Italy.
Environ Int. 2003 Jan;28(7):559-65. doi: 10.1016/s0160-4120(02)00081-8.
Isomer specific concentrations of individual polychlorinated biphenyls (PCBs) including toxic non-ortho (IUPAC 77, 126, 169) and mono-ortho (105, 118, 156) coplanar congeners were determined in the blubber of nine bottlenose dolphins (Tursiops truncatus) stranded along the Eastern Italian coast. The total PCB concentrations ranged from 3534 to 24375 ng/g wet wt. The PCB profile was dominated by congeners 138 and 153 collectively accounting for 55% of the total PCB concentrations. Among the most toxic congeners the order of abundance was 126>169>77. The mean total 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) equivalent of six coplanar PCBs in the blubber of bottlenose dolphins was 45596 pg/g. Non-ortho congeners contributed greater to the 2,3,7,8-TCDD toxic equivalents than mono-ortho members. Particularly, PCB 126 was the major contributor to the estimated toxic potency of PCBs in dolphins.
在沿意大利东海岸搁浅的9头宽吻海豚（瓶鼻海豚）的鲸脂中，测定了包括有毒非邻位（国际纯粹与应用化学联合会编号77、126、169）和单邻位（105、118、156）共面同系物在内的各多氯联苯（PCBs）异构体的特定浓度。PCBs总浓度范围为3534至24375纳克/克湿重。PCBs谱以同系物138和153为主，它们合计占PCBs总浓度的55%。在毒性最强的同系物中，丰度顺序为126>169>77。宽吻海豚鲸脂中6种共面PCBs的平均总2,3,7,8-四氯二苯并对二噁英（TCDD）当量为45596皮克/克。非邻位同系物对2,3,7,8-TCDD毒性当量的贡献大于单邻位同系物。特别是，PCB 126是海豚体内PCBs估计毒性效力的主要贡献者。
