AAA蛋白

AAA proteins.

作者信息

Lupas Andrei N, Martin Jörg

机构信息

Department of Protein Evolution, Max-Planck-Institute for Developmental Biology, Spemannstrasse 35, D-72076 Tübingen, Germany.

出版信息

Curr Opin Struct Biol. 2002 Dec;12(6):746-53. doi: 10.1016/s0959-440x(02)00388-3.

DOI:10.1016/s0959-440x(02)00388-3

PMID:12504679

Abstract

AAA proteins have entered the molecular realm after being known primarily for their wide range of different functions. Structural studies have highlighted the organization of their constituent ATPase domains and indicate that hexamerization in combination with unfoldase activity is a common underlying feature of this ubiquitous protein family.

摘要

AAA蛋白在主要因其广泛多样的不同功能为人所知之后，进入了分子领域。结构研究突出了其组成ATP酶结构域的组织方式，并表明六聚化与解折叠酶活性相结合是这个普遍存在的蛋白质家族的一个共同基本特征。