Floegel Ingrid, Haas Anton, El-Shabrawi Yosuf
Department of Ophthalmology, Karl Franzens University Graz, Graz, Austria.
Am J Ophthalmol. 2003 Jan;135(1):103-5. doi: 10.1016/s0002-9394(02)01849-4.
To report a case of acute multifocal placoid pigment epitheliopathy (AMPPE)-like lesion as an early presentation of subacute sclerosing panencephalitis (SSPE).
Observational case report.
A 21-year-old woman presented with a profound loss of vision in the left eye. The initial clinical picture was characterized by a whitish infiltration of the macular area and papillary edema in the left eye. Six days later multiple chorioretinal infiltrations were present in the peripheral fundus of the left eye, which led to the diagnosis of AMPPE.
During the following year, a gradual change in her personality developed. The diagnosis of SSPE was made by cerebrospinal fluid examination. Her clinical condition deteriorated rapidly, and she died.
AMPPE can be accompanied by central nervous system involvement. We wish to emphasize the importance of considering the diagnosis of SSPE in cases of AMPPE.
报告一例急性多灶性扁平状色素上皮病变（AMPPE）样病变作为亚急性硬化性全脑炎（SSPE）早期表现的病例。
观察性病例报告。
一名21岁女性因左眼视力严重丧失就诊。最初的临床表现为左眼黄斑区白色浸润和乳头水肿。六天后，左眼周边眼底出现多处脉络膜视网膜浸润，从而诊断为AMPPE。
在接下来的一年里，她的性格逐渐发生变化。通过脑脊液检查确诊为SSPE。她的临床状况迅速恶化，最终死亡。
AMPPE可能伴有中枢神经系统受累。我们希望强调在AMPPE病例中考虑SSPE诊断的重要性。
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