Brudet-Wickel C L, Hogeweg M, de Wolff-Rouendaal D
Doc Ophthalmol. 1982 Jan 29;52(3-4):241-50. doi: 10.1007/BF01675854.
A report is given of the fundus changes in a 17-year-old boy suffering from SSPE, which clinically first manifested itself by visual disturbances. At first the right eye showed extensive yellowish-white oedema at the posterior pole, surrounded by smaller round, yellow, partly confluent lesions, passing into a scarring stage in about ten days. Fluorescein angiography of the right eye was performed, both in the acute stage, which suggested a Harada syndrome, and in the scarring stage, which resembled a disseminated chorioretinitis. Three weeks later, during the development of the general neurological symptoms, the left eye developed the same fundus picture and course as the right eye. The condition of the patient rapidly deteriorated, leading to death five weeks after the onset of his visual complaints.
报告了一名17岁患有亚急性硬化性全脑炎（SSPE）男孩的眼底变化，该疾病临床上最初表现为视觉障碍。起初，右眼后极部出现广泛的黄白色水肿，周围有较小的圆形、黄色、部分融合的病变，约十天后进入瘢痕形成阶段。对右眼进行了荧光素血管造影，在急性期提示为原田综合征，在瘢痕形成期则类似播散性脉络膜视网膜炎。三周后，在出现全身神经症状期间，左眼出现了与右眼相同的眼底表现和病程。患者病情迅速恶化，在出现视觉症状后五周死亡。
