Purhonen Sinikka, Turunen Matti, Ruohoaho Ulla-Maija, Niskanen Minna, Hynynen Markku
Department of Anesthesiology and Intensive Care, Kuopio University Hospital, Finland.
Anesth Analg. 2003 Jan;96(1):91-6, table of contents. doi: 10.1097/00000539-200301000-00020.
Supplemental 80% oxygen administration halves the incidence of postoperative nausea and vomiting (PONV) in inpatients. Whether it prevents PONV after ambulatory surgery is unknown. We tested the efficacy of supplemental 80% oxygen in decreasing the incidence of PONV after ambulatory gynecologic laparoscopy. One hundred patients were given a standardized sevoflurane anesthetic. They were randomly assigned to two groups: routine oxygen administration with 30% oxygen, balance nitrogen (Group A); and supplemental oxygen with 80% oxygen, balance nitrogen (Group B). Oxygen was administered during surgery and up to 1 h after surgery. The incidence of nausea and vomiting and the need for rescue antiemetics did not differ between the groups in the postanesthesia care unit, in the Phase II unit, or during the 24-h follow-up. The overall incidence of nausea and vomiting during the first postoperative 24 h was 62% in Group A and 55% in Group B (P = 0.486). There were no differences in the recovery profiles and patient satisfaction between the groups. In this study, supplemental oxygen did not prevent PONV in patients undergoing ambulatory gynecologic laparoscopy.
Supplemental 80% oxygen administration during surgery and until 1 h after surgery compared with 30% oxygen administration did not prevent postoperative nausea and vomiting after ambulatory gynecologic laparoscopy.
对住院患者补充80%的氧气可使术后恶心呕吐（PONV）的发生率减半。但尚不清楚其能否预防门诊手术后的PONV。我们测试了补充80%的氧气对降低门诊妇科腹腔镜检查术后PONV发生率的效果。100例患者接受了标准化的七氟醚麻醉。他们被随机分为两组：常规给予30%的氧气，其余为氮气（A组）；补充80%的氧气，其余为氮气（B组）。手术期间及术后1小时内给予氧气。在麻醉后护理单元、II期护理单元或24小时随访期间，两组患者的恶心呕吐发生率及使用急救止吐药的需求无差异。术后24小时内，A组恶心呕吐的总发生率为62%，B组为55%（P = 0.486）。两组患者的恢复情况和患者满意度无差异。在本研究中，补充氧气并不能预防接受门诊妇科腹腔镜检查患者的PONV。
与给予30%的氧气相比，手术期间及术后1小时内补充80%的氧气并不能预防门诊妇科腹腔镜检查术后的恶心呕吐。
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