Tanino Masamichi, Mizuno Chiemi, Shiomi Takehiko, Shima Toshihide, Nakajo Shinobu, Hara Akinori, Hashimoto Kazuaki
Dept. of Internal Medicine, Saiseikai Suita Hospital.
Gan To Kagaku Ryoho. 2002 Dec;29(13):2545-8.
It is believed that multiple hepatic metastases from stomach cancer are highly refractory, and resistant to clinical treatment. In the present study, TS-1 neoadjuvant therapy administered orally in a single course brought about CR in the hepatic metastatic foci and PR in the primary foci, thus enabling grade A radical extirpation in a case of advanced stomach cancer. The patient continued to be treated on an ambulatory basis. His peri- and post-operative courses were satisfactory and the treatment was completed without the development of adverse effects.
人们认为，胃癌的多发性肝转移极难治疗，对临床治疗具有抗性。在本研究中，单疗程口服替吉奥新辅助治疗使肝转移灶达到完全缓解（CR），原发灶达到部分缓解（PR），从而使一例晚期胃癌患者能够进行A级根治性切除。该患者继续接受门诊治疗。其围手术期和术后过程均令人满意，治疗完成且未出现不良反应。
