Tokuhara Takaya, Hara Akinori, Takahashi Yuko, Harada Tomoaki, Izumi Nobuyuki, Iwamoto Shinji, Satake Kazunari
Dept. of Gastroenterological and General Surgery, Saiseikai Suita Hospital.
Gan To Kagaku Ryoho. 2004 Jun;31(6):917-9.
We report herein a case of heterochronous hepatic metastasis of gastric cancer that responded well to chemotherapy using TS-1. The patient was a 72-year-old man who underwent total gastrectomy for gastric cancer. Liver metastasis (S8, 4 cm in diameter) was found 3 months after surgery. TS-1 (100 mg/day) was administered orally everyday for a total of 33 weeks, after which the liver metastasis showed CR. Grade 2 fever and grade 2 dermatitis were the only adverse reactions observed, and the patient did not require hospitalization by discontinuing TS-1 administration. The present case suggests the usefulness of chemotherapy using TS-1.
我们在此报告一例胃癌异时性肝转移患者,其对使用替吉奥(TS-1)的化疗反应良好。该患者为一名72岁男性,因胃癌接受了全胃切除术。术后3个月发现肝转移(S8,直径4 cm)。每天口服替吉奥(100 mg/天),共33周,之后肝转移灶显示完全缓解(CR)。仅观察到2级发热和2级皮炎这两种不良反应,通过停用替吉奥治疗,患者无需住院。本病例提示了使用替吉奥化疗的有效性。