质子化多核苷酸结构。18. 寡聚胞苷酸与聚（G）的相互作用。
Protonated polynucleotide structures. 18. Interaction of oligocytidylates with poly (G).
作者信息
Haas B L, Guschlbauer W
出版信息
Nucleic Acids Res. 1976 Jan;3(1):205-18. doi: 10.1093/nar/3.1.205.
Abstract
The faculty for and degree of oligo(C)-poly(G) interaction is described as an essentially chain length - sensitive phenomenon. At neutral pH under suitable experimental conditions, oligocytidylates of chain length greater than four associate with poly(G) to form double-stranded structures, as does poly(C). The extent of complex formation increases with degree of polymerization. The complex at acid pH is shown to be triple-stranded, of stoicheometry 2C/1G. The observation of a 2G/1C artifact is discussed.
摘要
寡聚（C）-聚（G）相互作用的能力和程度被描述为一种本质上对链长敏感的现象。在合适的实验条件下，在中性pH值时，链长大于4的寡聚胞苷酸与聚（G）结合形成双链结构，聚（C）也是如此。复合物形成的程度随着聚合度的增加而增加。在酸性pH值下的复合物显示为化学计量比为2C/1G的三链结构。对2G/1C假象的观察进行了讨论。
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