质子化多核苷酸结构，20. 聚（dG）-聚（dC）与聚（rC）之间的相互作用。1.

Protonated polynucleotide structures, 20. Interaction between poly(dG)-poly(dC) and poly(rC).1.

作者信息

Haas B L, Sarocchi M T, Guschilbauer W

出版信息

Nucleic Acids Res. 1976 Jun;3(6):1549-59. doi: 10.1093/nar/3.6.1549.

DOI:10.1093/nar/3.6.1549

PMID:8771

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC343012/

Abstract

A study of the interaction between poly(dG)-poly(dC) and poly(rC) demonstrates that, at neutral pH and high ionic strength, there is replacement of the dC strand by poly(rC). At acid pH, formation of a triple-stranded complex which equally may involve the replacement phenomenon is observed. There is no evidence for interaction at neutral pH between poly(dG)-poly(dC) and oligo(rC), while a three-stranded complex is formed at acid pH. These data are consistent with the studies of comparative stabilities of double stranded deoxy or ribo polymers and deoxy-ribo hybrids.

摘要

一项关于聚（dG）-聚（dC）与聚（rC）之间相互作用的研究表明，在中性pH值和高离子强度下，聚（rC）会取代dC链。在酸性pH值下，会观察到形成一种同样可能涉及取代现象的三链复合物。没有证据表明在中性pH值下聚（dG）-聚（dC）与寡聚（rC）之间存在相互作用，而在酸性pH值下会形成三链复合物。这些数据与双链脱氧或核糖聚合物以及脱氧-核糖杂交体的相对稳定性研究一致。

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本文引用的文献

1

TRANSITIONS OF DNA HOMOPOLYMERS.DNA同聚物的转变

J Mol Biol. 1964 Sep;9:624-37. doi: 10.1016/s0022-2836(64)80171-6.

2

Comparative properties of DNA, RNA, and hybrid homopolymer pairs.DNA、RNA及杂交同聚物对的比较特性

Fed Proc. 1965 Nov-Dec;24(6):1446-57.

3

Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences.双链DNA与含有重复核苷酸序列的单链RNA之间三链复合物形成的特异性。

J Mol Biol. 1968 Oct 14;37(1):63-80. doi: 10.1016/0022-2836(68)90073-9.

4

Protonated polynucleotide structures. IX. Disproportionation of poly (G)-poly (C) in acid medium.质子化多核苷酸结构。IX. 聚（G）-聚（C）在酸性介质中的歧化作用。

Biopolymers. 1971;10(1):143-57. doi: 10.1002/bip.360100111.

5

Enzymatic and physical studies on the triplex dTn.dAn.rUn.对三链体dTn.dAn.rUn的酶学和物理学研究

Can J Biochem. 1973 Apr;51(4):436-49. doi: 10.1139/o73-051.

6

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Eur J Biochem. 1975 Feb 21;51(2):369-76. doi: 10.1111/j.1432-1033.1975.tb03937.x.

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