Zhang Xin, Wang Yixun, Wang Huiming
Department of Gynecology, Liaoning Provincial Tumor Hospital, Shenyang 110042, China.
Zhonghua Zhong Liu Za Zhi. 2002 May;24(3):294-6.
To evaluate the results of Gynatron low dose rate (LDR) brachytherapy for cancer of uterine cervix.
From April 1980 to June 1986, 136 patients with uterine cervical carcinoma were given radical radiotherapy through LDR afterloading irradiation and (60)Co external irradiation, compared with those through radium and high dose rate (HDR) intracavitary therapy.
All patients except 5 were followed up for 15 years with a follow-up rate of 96.3% (131/136). The overall 10-year survival rate was 63.5%. The 10-year survival rates of stage II and III patients were 83.9% and 43.2%. The frequency of proctitis and cystitis were 12.5% (17/136) and 9.6% (13/136).
Gynatron LDR system has achieved good results with tolerable complications including proctitis and cystitis which are more often than those of radium and less so than those of HDR.
评估Gynatron低剂量率（LDR）近距离放射治疗子宫颈癌的效果。
1980年4月至1986年6月，136例子宫颈癌患者接受了LDR后装照射联合（60）Co外照射的根治性放疗，并与镭疗和高剂量率（HDR）腔内治疗的患者进行比较。
除5例患者外，其余患者均随访15年，随访率为96.3%（131/136）。10年总生存率为63.5%。Ⅱ期和Ⅲ期患者的10年生存率分别为83.9%和43.2%。直肠炎和膀胱炎的发生率分别为12.5%（17/136）和9.6%（13/136）。
Gynatron LDR系统取得了良好的效果，并发症（包括直肠炎和膀胱炎）可耐受，其发生率高于镭疗，低于HDR。
