Gross Seth A., Katz Seymour
Division of Gastroenterology, Department of Medicine, North Shore University Hospital-New York University School of Medicine, 300 Community Drive, Manhasset, NY 11030, USA.
Curr Treat Options Gastroenterol. 2003 Feb;6(1):3-11. doi: 10.1007/s11938-003-0027-4.
Small bowel diverticulosis (SBD) is a rare entity. Most cases of diverticulosis are asymptomatic. SBD is often discovered incidentally during contrast studies and endoscopy. When patients report chronic gastrointestinal symptoms such as abdominal pain, bloating, flatulence, and anemia, SBD is often an overlooked diagnosis. Patients requiring treatment for SBD are those with complications such as malabsorption, hemorrhage, obstruction, and acute inflammation with abscess or rarely perforation. Malabsorption can be managed with broad-spectrum antibiotics and vitamin supplementation. Hemorrhage is treated conservatively with resuscitation efforts, but recurrent bleeding requires surgery. Enteroliths causing obstruction in the duodenum can be relieved by endoscopy, that is, by manipulation, but jejunoileal obstruction requires a resection. Pseudo- obstruction may be managed with prokinetics such as metoclopramide, erythromycin, and the 5-hydroxytryptamine 4 agonist tegaserod. Uncomplicated cases of SBD are treated with bowel rest and antibiotics. However, perforation or abscess formation not amenable to percutaneous drainage mandates surgical resection. Any patient with a triad of anemia, abdominal pain, and an abdominal radiograph with dilated loops of small bowel merits SBD in the differential diagnosis.
小肠憩室病(SBD)是一种罕见疾病。大多数憩室病病例无症状。SBD常在造影检查和内镜检查时偶然发现。当患者报告有腹痛、腹胀、肠胃气胀和贫血等慢性胃肠道症状时,SBD常是一个被忽视的诊断。需要治疗的SBD患者是那些有诸如吸收不良、出血、梗阻以及伴有脓肿的急性炎症或极少发生的穿孔等并发症的患者。吸收不良可用广谱抗生素和补充维生素来处理。出血通过复苏措施进行保守治疗,但反复出血则需要手术。导致十二指肠梗阻的肠石可通过内镜操作缓解,即通过手法,但空肠回肠梗阻则需要切除。假性梗阻可用促动力药如甲氧氯普胺、红霉素和5-羟色胺4激动剂替加色罗来处理。SBD的非复杂性病例采用肠道休息和抗生素治疗。然而,无法进行经皮引流的穿孔或脓肿形成则需要手术切除。任何有贫血、腹痛三联征以及腹部X线片显示小肠肠袢扩张的患者在鉴别诊断中都应考虑SBD。