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P2Ys go neuronal: modulation of Ca2+ and K+ channels by recombinant receptors.

作者信息

Boehm Stefan

机构信息

Institute of Pharmacology, University of Vienna, Waehringerstrasse 13a, A-1090 Vienna, Austria.

出版信息

Br J Pharmacol. 2003 Jan;138(1):1-3. doi: 10.1038/sj.bjp.0705044.

DOI:10.1038/sj.bjp.0705044
PMID:12522065
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1573656/
Abstract
摘要

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Attenuation of the P2Y receptor-mediated control of neuronal Ca2+ channels in PC12 cells by antithrombotic drugs.抗血栓药物对PC12细胞中P2Y受体介导的神经元Ca2+通道控制的减弱作用。
Br J Pharmacol. 2003 Jan;138(2):343-50. doi: 10.1038/sj.bjp.0705037.
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Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis.M电流通道的毒蕈碱调节恢复需要磷脂酰肌醇4,5-二磷酸的合成。
Neuron. 2002 Aug 1;35(3):507-20. doi: 10.1016/s0896-6273(02)00790-0.
4
Characterization and channel coupling of the P2Y(12) nucleotide receptor of brain capillary endothelial cells.脑毛细血管内皮细胞P2Y(12)核苷酸受体的特性及通道偶联
J Biol Chem. 2002 Aug 30;277(35):31390-400. doi: 10.1074/jbc.M110714200. Epub 2002 Jun 21.
5
Fine tuning of sympathetic transmitter release via ionotropic and metabotropic presynaptic receptors.通过离子型和代谢型突触前受体对交感神经递质释放进行精细调节。
Pharmacol Rev. 2002 Mar;54(1):43-99. doi: 10.1124/pr.54.1.43.
6
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J Biol Chem. 2001 Nov 2;276(44):41479-85. doi: 10.1074/jbc.M105912200. Epub 2001 Aug 23.
7
Molecular physiology of P2X receptors and ATP signalling at synapses.突触处P2X受体的分子生理学与ATP信号传导
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Nature. 2001 Jan 11;409(6817):202-7. doi: 10.1038/35051599.
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A voltage-independent calcium current inhibitory pathway activated by muscarinic agonists in rat sympathetic neurons requires both Galpha q/11 and Gbeta gamma.毒蕈碱激动剂在大鼠交感神经元中激活的一条电压非依赖性钙电流抑制途径需要Gαq/11和Gβγ两者参与。
J Neurosci. 2000 Aug 1;20(15):5623-9. doi: 10.1523/JNEUROSCI.20-15-05623.2000.