[原发性肝细胞癌中HLA-I抗原的表达]
[Expression of HLA-I antigens in primary hepatocellular carcinoma].
作者信息
Huang J, Cai M, Li G, Wei D, Tan Y
机构信息
Department of Immunology, School of Basic Medical Sciences, WCUMS, Chengdu 610041, China.
出版信息
Hua Xi Yi Ke Da Xue Xue Bao. 2001 Dec;32(4):495-6, 504.
PMID:12528529
Abstract
OBJECTIVE
To find out whether hepatocellular carcinoma (HCC) cells express HLA-I antigens.
METHODS
LSAB assay of immunohistochemistry was used to detect six frozen HCC specimens.
RESULTS
All the HCC cells have strong expression of HLA-I antigens.
CONCLUSION
In view of these data on the expression of HLA-I antigens, the authors deem it practical to develop HCC CTL vaccine.
摘要
目的
探究肝细胞癌（HCC）细胞是否表达HLA - I类抗原。
方法
采用免疫组织化学LSAB法检测6例冷冻的HCC标本。
结果
所有HCC细胞均有HLA - I类抗原的强表达。
结论
鉴于这些关于HLA - I类抗原表达的数据，作者认为开发HCC细胞毒性T淋巴细胞（CTL）疫苗具有可行性。
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