Acosta Edward P, King Jennifer R
Division of Clinical Pharmacology, University of Alabama at Birmingham, Birmingham, AL 35294-0019 , USA.
Clin Infect Dis. 2003 Feb 1;36(3):373-7. doi: 10.1086/345993. Epub 2003 Jan 14.
Interest in monitoring antiretroviral drug concentrations in human immunodeficiency virus-infected patients has gained considerable momentum in recent years. We present a potential method for integrating pharmacokinetic and phenotypic information that will assist clinicians in choosing optimal treatment regimens for their patients and that will provide an approach for the interpretation of antiretroviral plasma drug concentrations.
近年来，监测人类免疫缺陷病毒感染患者体内抗逆转录病毒药物浓度的研究受到了广泛关注。我们提出了一种整合药代动力学和表型信息的潜在方法，这将有助于临床医生为患者选择最佳治疗方案，并为解释抗逆转录病毒血浆药物浓度提供一种方法。
