Chen Z, Luo Z, Yang S
College of Stomatology, West China University of Medical Sciences.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2001 Feb;19(1):20-2.
The purpose of the experiment is to investigate the effect of fluoride dentifrices in China on the intact and artificial caries-like bovine enamels.
The artificial caries-like lesions were created by dipping the teeth into an acid buffered solution. Both the bovine intact enamels and the artificial caries-like enamels were assigned tooth brushing 20 times every half an hour with 3 kinds of fluoride dentifrices and one kind of non-fluoride dentifrices respectively. The amount of calcium dissolved by lactic acid was determined as the susceptibility of demineralization by atomic adsorption spectrometry (AAS).
The group treated with fluoride dentifrice showed significantly less demineralization than the non-fluoride group (P < 0.02). The effect of inhibition of acid solubility in artificial caries-like enamel after tooth brushing is significantly greater than that in intact enamel.
Fluoride dentifrices in this experiment can prevent both intact enamel and artificial caries-like enamel from acid solubility after tooth brushing, and it seems that the effect of the fluoride dentifrices on the redemineralization is greater than the reduction of enamel solubility.
本实验旨在研究中国市售含氟牙膏对完整牛牙釉质及人工龋样牛牙釉质的影响。
将牙齿浸入酸性缓冲溶液中制备人工龋样病变。将牛的完整牙釉质和人工龋样牙釉质分别用3种含氟牙膏和1种不含氟牙膏，每隔半小时刷牙20次。通过原子吸收光谱法（AAS）测定乳酸溶解的钙量，以此作为脱矿敏感性指标。
使用含氟牙膏的组脱矿程度明显低于不含氟牙膏组（P < 0.02）。刷牙后，含氟牙膏对人工龋样牙釉质酸溶解性的抑制作用明显大于对完整牙釉质的抑制作用。
本实验中的含氟牙膏在刷牙后可防止完整牙釉质和人工龋样牙釉质发生酸溶解，而且含氟牙膏对再矿化的作用似乎大于对牙釉质溶解性的降低作用。
