Petrie A, Bulman J S, Osborn J F
Eastman Dental Institute for Oral Health Care Sciences, University College London, London.
Br Dent J. 2003 Jan 11;194(1):17-21. doi: 10.1038/sj.bdj.4802405.
Consider the situation in which there is a single quantitative variable of interest that is measured on each individual on several different occasions. Typically, these occasions are defined time points (usually including pre-treatment as well as various post-treatment times), so that each individual contributes a series of readings. The main objective of the study may be to compare the responses on this variable when each individual has been assigned to one of two or more treatments groups.