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结核性输尿管狭窄的早期腔内泌尿外科治疗的作用

Role of early endourologic management of tuberculous ureteral strictures.

作者信息

Shin Ki Yong, Park Hyun Jun, Lee Jong Jin, Park Hae Young, Woo Young Nam, Lee Tchun Yong

机构信息

Department of Urology, College of Medicine, Hanyang University, Seoul, Korea.

出版信息

J Endourol. 2002 Dec;16(10):755-8. doi: 10.1089/08927790260472917.

Abstract

BACKGROUND AND PURPOSE

Tuberculous ureteral stricture causing progressive obstructive uropathy commonly complicates renal tuberculosis. The aim of our study was to evaluate the effectiveness of early ureteral stenting or percutaneous nephrostomy (PCN) in patients with tuberculous ureteral strictures.

PATIENTS AND METHODS

Seventy-seven patients (84 renal units) with tuberculous ureteral strictures were analyzed. We evaluated the final outcome of involved kidneys with three different managements: medication only (N = 37), medication plus ureteral stenting (N = 28), or medication plus PCN (N = 19).

RESULTS

The overall nephrectomy rate was 51%. In patients treated with medication only, the nephrectomy rate was 73%, whereas the nephrectomy rate was 34% in patients treated with medication plus early ureteral stenting or PCN. The rate of reconstructive surgery for ureteral strictures also was significantly different for patients treated with medication only (8%) and those receiving medication plus early ureteral stenting or PCN (49%). Spontaneous resolution of the strictures was noted in 6 of the 12 renal units that were managed with early ureteral stenting.

CONCLUSIONS

Early ureteral stenting or PCN in patients with tuberculous ureteral strictures may increase the opportunity for later reconstructive surgery and decrease the likelihood of renal loss.

摘要

背景与目的

结核性输尿管狭窄导致进行性梗阻性尿路病,常使肾结核复杂化。我们研究的目的是评估早期输尿管支架置入术或经皮肾造瘘术(PCN)对结核性输尿管狭窄患者的有效性。

患者与方法

分析了77例(84个肾单位)结核性输尿管狭窄患者。我们采用三种不同的治疗方法评估受累肾脏的最终结局:单纯药物治疗(N = 37)、药物治疗加输尿管支架置入术(N = 28)或药物治疗加经皮肾造瘘术(N = 19)。

结果

总体肾切除率为51%。单纯药物治疗的患者肾切除率为73%,而药物治疗加早期输尿管支架置入术或经皮肾造瘘术的患者肾切除率为34%。单纯药物治疗的患者(8%)与接受药物治疗加早期输尿管支架置入术或经皮肾造瘘术的患者(49%)相比,输尿管狭窄重建手术率也有显著差异。在12个接受早期输尿管支架置入术治疗的肾单位中,有6个出现狭窄自发缓解。

结论

结核性输尿管狭窄患者早期行输尿管支架置入术或经皮肾造瘘术可能增加后期重建手术的机会,并降低肾丢失的可能性。

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