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烧伤微生物学领域有哪些新进展?2000年詹姆斯·莱恩纪念奖论文

What's new in burn microbiology? James Laing Memorial Prize Essay 2000.

作者信息

Edwards-Jones Valerie, Greenwood John E

机构信息

Department of Biological Sciences, Manchester Metropolitan University, Chester Street, M1 5GD, Manchester, UK.

出版信息

Burns. 2003 Feb;29(1):15-24. doi: 10.1016/s0305-4179(02)00203-6.

Abstract

A variety of factors contribute to the development of infection in burned patients. The role of wound management procedures, risk factors associated with infection, typical bacterial pathogens and associated exotoxins, current problems with antibiotic resistance, wound sampling and rare complications of infection are described. The use of new novel treatments that are currently being developed, such as cell signalling molecules and the increasing use of natural antimicrobial agents, for example honey, papaya fruit and tea-tree oil are discussed. The impact of new methods for earlier detection of infectious agents that could change future practices in burn care is also described.

摘要

多种因素促使烧伤患者发生感染。本文描述了伤口处理程序的作用、与感染相关的危险因素、典型的细菌病原体及相关外毒素、当前抗生素耐药性问题、伤口采样以及感染的罕见并发症。文中还讨论了目前正在研发的新型治疗方法的应用,如细胞信号分子,以及天然抗菌剂(如蜂蜜、木瓜果实和茶树油)使用的增加。文中也描述了能够改变未来烧伤护理实践的感染病原体早期检测新方法的影响。

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