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成人急性中耳炎与面神经麻痹

Acute otitis media and facial nerve paralysis in adults.

作者信息

Redaelli de Zinis Luca O, Gamba Paolo, Balzanelli Cristiano

机构信息

Department of Otolaryngology, University of Brescia, Italy.

出版信息

Otol Neurotol. 2003 Jan;24(1):113-7. doi: 10.1097/00129492-200301000-00022.

Abstract

OBJECTIVE

The pathophysiology and treatment of facial nerve paralysis associated with acute otitis media are still under debate. The objective of this study was to review treatment strategies and extent of recovery in adult patients with the aim of defining a standard treatment protocol for this rare pathologic condition.

STUDY DESIGN

Retrospective chart review.

SETTING

University hospital, tertiary referral center.

PATIENTS

Between 1993 and 2000, 11 patients were admitted for facial nerve paralysis secondary to acute otitis media. There were six women and five men without a history of chronic middle ear disease, who ranged in age from 21 to 71 years. Facial palsy was graded with the House-Brackmann scale: four patients had Grade III palsy, six had Grade IV palsy, and one patient had Grade V palsy. Bacteriologic examination of middle ear fluid was performed in four patients Streptococcus pneumoniae was observed in one patient, and the remaining three cultures were negative.

INTERVENTIONS

All patients were treated with parenteral ampicillin-sulbactam or a third-generation cephalosporin in conjunction with oral or intravenous corticosteroids, except in a single patient with diabetes mellitus who received antibiotics alone. Myringotomy alone or with ventilation tube application was performed in eight patients. A simple mastoidectomy without facial nerve decompression was used in a patient with sudden impairment to Grade VI paralysis and worsening otitis after an initial improvement.

RESULTS

Normal facial function returned in all patients, independently of the grade of the paralysis, the treatment strategy, or the outcome of the middle ear disease. The time of recovery varied from 2 weeks to 3 months, except for one patient who underwent mastoidectomy and in whom normal function returned in 10 months.

CONCLUSIONS

The treatment of facial nerve paralysis secondary to otitis media should be as conservative as possible, using antibiotics and corticosteroids. Myringotomy and a ventilation tube should be added when spontaneous perforation of the tympanic membrane is not present. Mastoidectomy should be performed only when it is necessary to treat otitis media. Facial nerve decompression should not be necessary.

摘要

目的

与急性中耳炎相关的面神经麻痹的病理生理学及治疗方法仍存在争议。本研究的目的是回顾成年患者的治疗策略及恢复程度,旨在为这种罕见的病理状况确定标准治疗方案。

研究设计

回顾性病历审查。

研究地点

大学医院,三级转诊中心。

患者

1993年至2000年间,11例因急性中耳炎继发面神经麻痹入院的患者。6名女性和5名男性,无慢性中耳疾病史,年龄在21岁至71岁之间。面神经麻痹采用House-Brackmann量表分级:4例为Ⅲ级麻痹,6例为Ⅳ级麻痹,1例为Ⅴ级麻痹。4例患者进行了中耳积液细菌学检查,1例患者检出肺炎链球菌,其余3例培养结果为阴性。

干预措施

所有患者均接受胃肠外氨苄西林-舒巴坦或第三代头孢菌素联合口服或静脉注射皮质类固醇治疗,但1例糖尿病患者仅接受了抗生素治疗。8例患者单独或联合置管进行了鼓膜切开术。1例患者最初病情改善后突然出现Ⅵ级麻痹且中耳炎加重,接受了单纯乳突切除术,未进行面神经减压。

结果

所有患者均恢复了正常面部功能,与麻痹分级、治疗策略或中耳疾病的结果无关。恢复时间从2周至3个月不等,但1例接受乳突切除术的患者在10个月后恢复了正常功能。

结论

中耳炎继发面神经麻痹的治疗应尽可能保守,使用抗生素和皮质类固醇。鼓膜未自发穿孔时应加用鼓膜切开术和通气管。仅在治疗中耳炎必要时才应进行乳突切除术。无需进行面神经减压。

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