Fichera Piergabriele, Bruschini Luca, Berrettini Stefano, Capobianco Silvia, Fiacchini Giacomo
Department of Surgical Pathology, Medical, Molecular and Critical Area, ENT Section, Pisa University Hospital, Via Paradisa, 2, 56126 Pisa, Italy.
Audiol Res. 2023 Nov 8;13(6):889-897. doi: 10.3390/audiolres13060077.
Acute otitis media (AOM) is one of the most common ENT diseases in children. In the antibiotic/post-antibiotic era, facial paralysis is a very rare complication of AOM (0.004-0.005%). Despite the rarity of this complication, it should be known by all physicians for proper therapeutic management to avoid serious sequelae. The aim of this review is to provide a management guide based on the current literature.
Fifteen studies published between 2000 and 2022 were selected, including 120 patients (62 M/58 F) with an average age of 4.96 years old (range = 4 months-16 years; SD: 4.2). The paralysis frequently has a sudden onset and is of a severe grade (medium House-Brackmann (HB) score at onset: 4.68; SD: 0.5); however, it tends to have an almost complete recovery in most patients (88.49% HB 1 at follow-up).
Its first-line treatment must be based on the use of antibiotics (beta-lactam antibiotics as penicillins or cephalosporins). Corticosteroids should be used concomitantly for their anti-inflammatory and neuroprotective actions; however, there is no unanimity between authors about their application. Myringotomy, with or without ventilation tube insertion, is indicated in cases where the tympanic membrane is intact. Other kinds of surgery should be performed only in patients who have a worsening of their AOM symptoms or a worsening in HB score even with clinical treatment.
The obtained data show that a conservative treatment can be sufficient for complete recovery in most patients, and it is preferred as the first-line therapy. Mastoidectomy should be performed only in patients with acute mastoiditis and without symptom improvement after a conservative approach. There are insufficient data in the current literature to provide clear selection criteria for patients who need to undergo mastoidectomy with facial nerve decompression. The choice of this treatment is based on an individual center expertise. Further studies are needed to clarify the role of corticosteroids and the role of facial nerve decompression in this clinical scenario.
急性中耳炎(AOM)是儿童最常见的耳鼻喉科疾病之一。在抗生素/抗生素后时代,面瘫是AOM一种非常罕见的并发症(0.004 - 0.005%)。尽管这种并发症罕见,但所有医生都应了解,以便进行适当的治疗管理,避免严重后遗症。本综述的目的是根据当前文献提供一份管理指南。
选取了2000年至2022年间发表的15项研究,包括120例患者(62例男性/58例女性),平均年龄4.96岁(范围 = 4个月 - 16岁;标准差:4.2)。面瘫通常突然发作且程度严重(发病时House - Brackmann(HB)评分为中等:4.68;标准差:0.5);然而,大多数患者倾向于几乎完全恢复(随访时88.49%的患者HB评分为1级)。
其一线治疗必须基于使用抗生素(β - 内酰胺类抗生素,如青霉素或头孢菌素)。应同时使用皮质类固醇,因其具有抗炎和神经保护作用;然而,作者们对于其应用尚未达成一致。在鼓膜完整的情况下,建议进行鼓膜切开术,可插入或不插入通气管。仅在AOM症状恶化或即使经过临床治疗HB评分仍恶化的患者中进行其他类型的手术。
获得的数据表明,保守治疗对大多数患者的完全恢复可能就足够了,并且作为一线治疗更受青睐。仅在患有急性乳突炎且保守治疗后症状无改善的患者中进行乳突切除术。当前文献中没有足够的数据为需要进行面神经减压的乳突切除术患者提供明确的选择标准。这种治疗的选择基于各个中心的专业知识。需要进一步研究以阐明皮质类固醇的作用以及面神经减压在这种临床情况下的作用。