Schachner A, Wurzel M, Levy M J
Isr J Med Sci. 1976 Jan;12(1):21-7.
Ten patients suffering from tight mitral stenosis with severe pulmonary hypertension were operated on and followed up for one to nine years after operation. There was no operative or postoperative mortality. Postoperative hemodynamic studies were performed on seven of the 10 patients. One patient was evaluated twice--one month and seven months after surgery. The condition of all patients improved after operation and regression of severe to extreme pulmonary hypertension was documented in the seven patients on whom the hemodynamic studies were repeated. Hemodynamic and clinical improvement was greatest in young patients with a shorter duration of disease and a normal sinus rhythm prior to operation. The results indicate that a severe degree of pulmonary vascular resistance in mitral stenosis is largely reversible, provided that the obstruction is adequately relieved.
对10例患有严重二尖瓣狭窄并伴有重度肺动脉高压的患者进行了手术，并在术后进行了1至9年的随访。手术期间及术后均无死亡病例。10例患者中有7例进行了术后血流动力学研究。1例患者在术后1个月和7个月进行了两次评估。所有患者术后情况均有改善，对7例重复进行血流动力学研究的患者，记录到重度至极重度肺动脉高压出现了消退。在术前病程较短且为正常窦性心律的年轻患者中，血流动力学和临床改善最为显著。结果表明，只要梗阻得到充分解除，二尖瓣狭窄中重度的肺血管阻力在很大程度上是可逆的。
