Tsao May N, Schwartz Michael L, Bernstein Mark, Halliday William C, Lightstone Alex W, Hamilton Mark G, Jaywant Satish, Laperriere Normand
Department of Radiation Oncology, Toronto-Sunnybrook Regional Cancer Centre, Ontario, Canada.
J Neurosurg. 2003 Jan;98(1):169-74. doi: 10.3171/jns.2003.98.1.0169.
Capillary hemangiomas are rare benign vascular tumors that tend to occur in children. Whereas the majority of hemangiomas may regress spontaneously, those associated with functional sequelae or severe symptoms may require treatment. Two patients with capillary hemangiomas of the cavernous sinus that caused neurological symptoms were treated with fractionated stereotactic radiation therapy. Both hemangiomas had shown a progressive increase in size during observation before radiation therapy; both tumors regressed after radiotherapy. Up to the time of the last follow-up evaluation both patients experienced symptomatic relief after radiation. One patient's tumor remains in complete remission and the second tumor continues to demonstrate minor residual contrast enhancement without progression. The authors conclude that fractionated stereotactic radiation therapy is a useful treatment modality in the management of symptomatic capillary hemangiomas when these tumors arise in regions of the brain or skull base in which a complete resection cannot be accomplished.
毛细血管瘤是罕见的良性血管肿瘤，多见于儿童。虽然大多数血管瘤可自发消退，但那些伴有功能后遗症或严重症状的血管瘤可能需要治疗。两名患有海绵窦毛细血管瘤并导致神经症状的患者接受了分次立体定向放射治疗。在放疗前观察期间，两个血管瘤的大小均呈渐进性增大；放疗后两个肿瘤均缩小。截至最后一次随访评估时，两名患者放疗后症状均缓解。一名患者的肿瘤仍完全缓解，另一个肿瘤仍有轻微残留对比增强，但无进展。作者得出结论，当这些肿瘤出现在无法完全切除的脑或颅底区域时，分次立体定向放射治疗是治疗有症状毛细血管瘤的一种有效治疗方式。
