Williams A O, Loewenson R B, Lippert D M, Resch J A
Stroke. 1975 Jul-Aug;6(4):395-401. doi: 10.1161/01.str.6.4.395.
Factors which are known to be associated with cerebral atherosclerosis were evaluated in Nigerian Africans. Of 465 autopsied adult Nigerians, 62 (13%) had cerebral atherosclerosis. The frequency and severity of atherosclerosis among Nigerians with hypertension, particularly male subjects, were higher than in normotensives. Although there was a similar frequency of hypertension among autopsied Nigerian and Minnesota Caucasian populations, the severity and extent of atherosclerosis were greater in the Minnesota Caucasian populations, the severity and extent of atherosclerosis were greater in the Minnesota population. The relatively short duration of hypertension in the Nigerian before death might be an important factor which did not permit progressive development of cerebral atherosclerosis. Other factors which predisposed the Nigerian to increased frequency and severity of atherosclerosis included increased heart weight and diabetes mellitus. The relatively low frequency of cerebrovascular disease in the Nigerian may be explained on the basis of a low degree of cerebral atherosclerosis and relatively short duration of hypertension.
在尼日利亚非洲人中，对已知与脑动脉粥样硬化相关的因素进行了评估。在465名接受尸检的成年尼日利亚人中，62人（13%）患有脑动脉粥样硬化。患有高血压的尼日利亚人，尤其是男性，动脉粥样硬化的发生率和严重程度高于血压正常者。尽管在接受尸检的尼日利亚人群和明尼苏达白种人群中高血压的发生率相似，但明尼苏达白种人群中动脉粥样硬化的严重程度和范围更大。尼日利亚人在死前高血压持续时间相对较短，这可能是一个重要因素，使得脑动脉粥样硬化无法进行性发展。其他使尼日利亚人动脉粥样硬化发生率和严重程度增加的因素包括心脏重量增加和糖尿病。尼日利亚人脑血管疾病发生率相对较低，这可能是由于脑动脉粥样硬化程度较低以及高血压持续时间相对较短。
