Ganten M, Encke J, Flosdorff P, Grüber-Hoffmann B, Erb G, Hansmann J
Abt.Radiodiagnostik, Radiologische Uniklinik Heidelberg.
Radiologe. 2003 Jan;43(1):26-33. doi: 10.1007/s00117-002-0851-x.
Evaluation of typical MRI-findings in patients with Crohn's disease receiving therapy. Correlation with the course of disease.
81 follow-up MRI-studies in 25 patients conducted within a period of 3 weeks to 4 years were evaluated retrospectively. Therapy consisted in various combinations of antibiotics and immunosuppressive agents and if necessary operation. The findings of the MRI-studies were correlated with clinical data (e.g.operation of Crohn's complications) and the subjective perception during therapy.
The morphological substrate of Crohn's disease in the Hydro-MRI images is reliably detected. Especially in a delineation of extraluminal changes MRI is superior to endoscopy and enteroclysis. Independent from clinical symptoms short- and mid-term follow-up showed inflammatory changes of the intestinal wall in all 25 patients. In 24/81 studies there was persistence or even progression of Crohn's disease in the MRI-studies, although patients were free of symptoms by the time of image acquisition.
Hydro-MRI is a modality for the evaluation of inflammatory changes in patients with Crohn's disease. Independent from clinical symptoms persistence of Crohn's disease is detectable.
评估接受治疗的克罗恩病患者的典型磁共振成像（MRI）表现，并与疾病进程进行相关性分析。
回顾性评估了25例患者在3周至4年期间进行的81次MRI随访研究。治疗包括抗生素和免疫抑制剂的各种联合应用，必要时进行手术。MRI研究结果与临床数据（如克罗恩病并发症的手术情况）及治疗期间的主观感受进行了相关性分析。
在水成像MRI图像中能可靠地检测到克罗恩病的形态学基础。尤其是在显示肠腔外变化方面，MRI优于内镜检查和小肠灌肠造影。与临床症状无关，短期和中期随访显示所有25例患者的肠壁均有炎症改变。在81项研究中的24项中，尽管在图像采集时患者无症状，但MRI研究显示克罗恩病持续存在甚至进展。
水成像MRI是评估克罗恩病患者炎症变化的一种方法。与临床症状无关，可检测到克罗恩病的持续存在。
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