[低温各向同性热解碳人工心脏瓣膜材料的表面改性]

[Surface modification of low temperature isotropic pyrolytic carbon artificial heart valve material].

作者信息

Huang N, Yang P, Leng Y

机构信息

Department of Material Engineering, Southwest Jiaotong University, Chengdu 610031.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 1999 Jun;16(2):127-31.

PMID:12552646

Abstract

In this study, nitrogen ion implantation and titanium oxide film synthesized by ion beam enhanced deposition were adopted to treat low temperature isotropic pyrolytic carbon (LTIC). The chemical composition and valence state of the modified layer were determined by X-ray photoelectron spectroscopy (XPS) and Auger eletron spectroscopy (AES). The electric resisitance and the surface energy were measured by the four-probe system and the contact angle method respectively. The blood compatibility of the modified LTIC was evaluated by clotting time measurement and platelet adhesion test. The results showed that carbon-nitride was formed on the LTIC surface after N+ ion implantation, which had some effect on the improvement of blood compatibility, and a significant improvement of blood compatibility of LTIC coated by TiO2-x film was verified.

摘要

在本研究中，采用氮离子注入和离子束增强沉积合成的二氧化钛薄膜对低温各向同性热解碳（LTIC）进行处理。通过X射线光电子能谱（XPS）和俄歇电子能谱（AES）确定改性层的化学成分和价态。分别用四探针系统和接触角法测量电阻和表面能。通过凝血时间测量和血小板黏附试验评估改性LTIC的血液相容性。结果表明，N⁺离子注入后LTIC表面形成了碳氮化物，这对血液相容性的改善有一定作用，并且证实了TiO₂₋ₓ薄膜包覆的LTIC的血液相容性有显著改善。