Studies in the synthesis of vernolepin. A Diels-Alder approach to the angularly functionalized AB system.
作者信息
Danishefsky S, Schuda P, Kato K
出版信息
J Org Chem. 1976 Apr 2;41(7):1081-8. doi: 10.1021/jo00869a001.
PMID:1255288
Abstract
摘要
相似文献
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Studies in the synthesis of vernolepin. A Diels-Alder approach to the angularly functionalized AB system.卫农菌素的合成研究。一种用于角官能化AB体系的狄尔斯-阿尔德方法。
J Org Chem. 1976 Apr 2;41(7):1081-8. doi: 10.1021/jo00869a001.
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Synthesis of sesquiterpene antitumor lactones. 6. cis-8a-Vinyloctahydro-3H-2-benzopyran-3,7-dione, a precursor to vernolepin.倍半萜抗肿瘤内酯的合成。6. 顺式-8a-乙烯基八氢-3H-2-苯并吡喃-3,7-二酮，苦鬼臼毒素的前体。
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Synthesis of a cytotoxic vernolepin prototype. Ozonization of silyloxyalkenes.一种细胞毒性藜芦醚原药的合成。硅烷氧基烯烃的臭氧化反应。
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Letter: A remarkable epoxide opening. An expeditious synthesis of vernolepin and vernomenin.信函：一个引人注目的环氧化合物开环反应。藜芦苦素和藜芦明宁的快速合成。
J Am Chem Soc. 1976 May 12;98(10):3028-30. doi: 10.1021/ja00426a066.
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(+/-)-Deoxyvernolepin. A cytotoxic vernolepin prototype.（±）-脱氧斑鸠菊素。一种具有细胞毒性的斑鸠菊素原型。
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Model studies directed toward the total synthesis of vernolepin. III. Synthesis of the alpha-methylene-delta-valerolactone ab ring model.针对卫矛醇内酯全合成的模型研究。III. α-亚甲基-δ-戊内酯AB环模型的合成。
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Synthesis of mono- and bifunctional alpha-methylene lactone systems as potential tumor inhibitors.作为潜在肿瘤抑制剂的单官能和双官能α-亚甲基内酯系统的合成。
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Sesquiterpene lactones: total synthesis of (+/-)-vernolepin and (+/-)-vernomenin.
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Synthesis of delta-lactones from cyclohexenones. Preparation of a vernolepin analog.由环己烯酮合成δ-内酯。制备一种藜芦素类似物。
J Org Chem. 1975 Oct 3;40(20):2970-1. doi: 10.1021/jo00908a031.
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