Lim J S, Proudfit W L, Sones F M
Am J Cardiol. 1975 Aug;36(2):131-5. doi: 10.1016/0002-9149(75)90515-9.
The prognosis of 141 patients with obstructive left main coronary artery disease was studied. The patients were followed up for 5 to 10 years from the date of coronary arteriography. The 5 year cardiac mortality rate was 51 percent. During the first 3 years after diagnosis, the mortality rate was especially high, 21.9, 34.7 and 43 percent, respectively. Among patients who died in the 1st year after diagnosis, evidence of left ventricular hypertrophy or conduction delay in the electrocardiogram and multiple vessel involvement indicated poor prognosis. Severe angina pectoris, evidence of congestive heart failure and generalized decrease in left ventricular contractility increased the 5 year mortality rate. More than 97 percent of the total patient population had additional lesions elsewhere in the coronary arteries.
对141例左主冠状动脉阻塞性疾病患者的预后进行了研究。自冠状动脉造影之日起，对这些患者进行了5至10年的随访。5年心脏死亡率为51%。在诊断后的头3年中，死亡率尤其高，分别为21.9%、34.7%和43%。在诊断后第1年死亡的患者中，心电图显示左心室肥厚或传导延迟以及多支血管受累提示预后不良。严重心绞痛、充血性心力衰竭的证据以及左心室收缩力普遍下降增加了5年死亡率。超过97%的患者在冠状动脉其他部位还有额外病变。
