Macran Susan, Weatherly Helen, Kind Paul
Outcomes Research Group, Centre for Health Economics, Alcuin College, University of York, Heslington, United Kingdom.
Med Care. 2003 Feb;41(2):218-31. doi: 10.1097/01.MLR.0000044901.57067.19.
The relative performance of three widely used generic health status measures (EQ-5D, a modified HUI3 [mHUI3], and SF-12) was compared within a general population sample.
Data were taken from a cohort of persons identified from the patient list of a large general practice in York, UK. Two-way comparisons were made between EQ-5D and mHUI3 and EQ-5D and SF-12. The measures were assessed in terms of their practical viability, coverage, and discrimination. Practical viability was evaluated in terms of the extent of missing responses and the proportion indicating difficulty with a measure. Coverage examined the range of responses across the items in the measures. Discrimination examined the capacity of the measures to discriminate between persons according to their self-reported morbidity and socioeconomic status.
One thousand one hundred twenty-six persons completed a postal questionnaire containing EQ-5D and either mHUI3 (n = 593) or SF-12 (n = 533). Missing responses were low across all three instruments. SF-12 showed a broad distribution of responses across its items however, responses on the mHUI3 hearing, speech and dexterity dimensions and the EQ-5D self-care dimension were highly skewed, with few persons reporting problems. In terms of summary scores, mHUI3 identified more mild health states than EQ-5D. EQ-5D and mHUI3 showed slightly better discrimination than SF-12.
Despite the inherent differences in their descriptive systems and scoring functions, no one instrument performed better or worse than the other with respect to the criteria applied in this study. Some of the issues to be considered when choosing a population health measure are discussed.
在一个普通人群样本中比较三种广泛使用的一般健康状况测量工具(EQ-5D、改良的健康效用指数3 [mHUI3]和SF-12)的相对性能。
数据取自英国约克郡一家大型全科诊所患者名单中确定的一组人群。对EQ-5D与mHUI3以及EQ-5D与SF-12进行了双向比较。从实际可行性、覆盖范围和区分度方面对这些测量工具进行了评估。实际可行性根据缺失回答的程度以及表示使用某一测量工具存在困难的比例来评估。覆盖范围考察了测量工具各项目的回答范围。区分度考察了测量工具根据自我报告的发病率和社会经济状况区分人群的能力。
1126人完成了一份包含EQ-5D以及mHUI3(n = 593)或SF-12(n = 533)的邮寄问卷。所有三种工具的缺失回答率都很低。SF-12各项目的回答分布广泛,然而,mHUI3听力、言语和灵巧度维度以及EQ-5D自我护理维度的回答高度偏态,很少有人报告有问题。就汇总分数而言,mHUI3识别出的轻度健康状态比EQ-5D更多。EQ-5D和mHUI3的区分度略优于SF-12。
尽管它们在描述系统和评分功能上存在固有差异,但就本研究应用的标准而言,没有一种工具表现得比其他工具更好或更差。讨论了选择人群健康测量工具时需要考虑的一些问题。