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经食管程控心房刺激在不明原因脑血管意外评估中的价值

[Value of transesophageal programmed atrial stimulation in the evaluation of unexplained cerebrovascular accidents].

作者信息

Brembilla-Perrot B, Blangy H, Holban I, Houriez P, Claudon O, Rizk J, Mauferon J B, Clavel A

机构信息

CHU de Brabois, 54500 Vandoeuvre-Les-Nancy.

出版信息

Ann Cardiol Angeiol (Paris). 1999 Feb;48(2):103-8.

Abstract

Certain embolic cerebrovascular accidents can be explained by the development of paroxysmal atrial fibrillation. When noninvasive complementary investigations are negative, programmed atrial stimulation can be proposed to detect increased atrial vulnerability. The objective of this study was to evaluate the reliability of this method performed via a transoesophageal approach in 59 subjects presenting with an embolic cerebrovascular accident and who were in sinus rhythm at the time of the accident. Seven of these patients had a history of paroxysmal atrial fibrillation (AF) or atrial tachycardia (AT) (group I). Three of these seven patients also presented AV nodal reentrant junctional tachycardia. The other 52 patients had no history of arrhythmia and their Holter recording did not reveal any episodes of sustained atrial tachycardia (group II). Transoesophageal programmed atrial stimulation used up to 2 extrastimuli under baseline conditions and during Isuprel infusion. The following results were obtained: sustained atrial tachycardia (> 1 min) was induced in all patients of group 1, 3 of them also presented inducible junctional tachycardias. 14 patients of group II (27%) presented inducible supraventricular tachycardia: atrial tachycardia in 7 cases. Patients in group II with inducible AT presented either heart disease (n = 3) or minor abnormalities on the Holter recording (runs of atrial premature complexes or sinus pauses (n = 3). Two of these patients subsequently developed sustained atrial fibrillation during follow-up. In 25 patients with normal Holter recording and no heart disease, programmed atrial stimulation induced junctional tachycardia in 4 cases. In conclusion, transoesophageal electrophysiological investigation is a useful way to identify various forms of supraventricular tachycardia able to explain an embolic cerebrovascular accident. The considerable incidence of inducible AV nodal reentrant junctional tachycardia must be emphasized, while the incidence of atrial fibrillation is much lower than during intracardiac investigations.

摘要

某些栓塞性脑血管意外可由阵发性心房颤动的发生来解释。当无创性辅助检查结果为阴性时,可采用程控心房刺激来检测心房易损性增加。本研究的目的是评估经食管途径对59例发生栓塞性脑血管意外且在意外发生时为窦性心律的患者进行该方法的可靠性。其中7例患者有阵发性心房颤动(AF)或心房心动过速(AT)病史(I组)。这7例患者中有3例还出现房室结折返性交界性心动过速。另外52例患者无心律失常病史,其动态心电图记录未发现任何持续性心房心动过速发作(II组)。在基线条件下和静脉滴注异丙肾上腺素期间,经食管程控心房刺激使用最多2个额外刺激。获得了以下结果:I组所有患者均诱发出持续性心房心动过速(>1分钟),其中3例还诱发出可诱导的交界性心动过速。II组14例患者(27%)诱发出可诱导的室上性心动过速:7例为心房心动过速。II组中诱发出心房心动过速的患者要么患有心脏病(n = 3),要么动态心电图记录有轻微异常(心房早搏连发或窦性停搏,n = 3)。其中2例患者在随访期间随后发生了持续性心房颤动。在25例动态心电图记录正常且无心脏病的患者中,程控心房刺激在4例中诱发出交界性心动过速。总之,经食管电生理检查是识别各种能够解释栓塞性脑血管意外的室上性心动过速的有用方法。必须强调可诱导的房室结折返性交界性心动过速的发生率相当高,而心房颤动的发生率远低于心内检查时。

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