Massias P, Moreau J F, Segond P, Bisson M
J Radiol Electrol Med Nucl. 1976 Jan;57(1):23-30.
Radiological diagnosis of Paget's disease which is based on hypertrophy of the osseous cortex, osteocondensation and a fibrillary appearance of the cancellous bone, can be rendered difficult when there is superadded demineralization. This is usual in the initial phase of the condition and take on the form of circumscribed osteoporosis. Such an appearance can however be misleading owing to its wide extent or to the number of localizations, as was the case in two of our cases; the diagnosis of Paget's disease must then be established from histological criteria. Besides this demineralization which is directly related to the morbid process in Paget's disease, calcium deficiency is known to modify the clinical and radiological symptomatology of Paget's disease. Our first two cases illustrate this fact and the remarkable effectiveness of "remineralization" therapy in such cases.
基于骨皮质肥大、骨质致密以及松质骨呈纤维状外观的佩吉特病的放射学诊断,当出现叠加的骨质脱矿时可能会变得困难。这在该病的初始阶段很常见,表现为局限性骨质疏松。然而,由于其范围广泛或部位数量众多,这种表现可能会产生误导,我们的两个病例就是如此;此时必须根据组织学标准来确立佩吉特病的诊断。除了这种与佩吉特病发病过程直接相关的骨质脱矿外,已知钙缺乏会改变佩吉特病的临床和放射学症状。我们的前两个病例说明了这一事实以及“再矿化”疗法在这类病例中的显著效果。