Hémery Y, Broustet H, Guiraudet O, Schiano P, Godreuil C, Plotton C, Ollivier J P
Service de pathologie cardiovasculaire, HIA du Val-de-Grâce, 74, boulevard de Port-Royal, 75230 Paris, France.
Ann Cardiol Angeiol (Paris). 2000 Dec;49(8):473-9.
Cardiovascular disease is the main cause of mortality in chronic alcoholics. There is a clear association between excessive alcohol consumption and the risk of sudden cardiac death. The pro-arrhythmogenic effect of ethanol could be responsible for some of these cases of arrhythmia and sudden death in subjects with an alcoholic cardiomyopathy and also in those with an apparently normal heart. In any case of supraventricular or ventricular arrhythmia in a chronic alcoholic or in an occasional heavy drinker, the potential role of alcohol consumption in the initiation of these disorders should be considered. In all cases, patient management consists of detoxification and abstaining from alcohol consumption, but the withdrawal period is particularly critical as regards the risk of ventricular arrhythmias.
心血管疾病是慢性酗酒者死亡的主要原因。过量饮酒与心源性猝死风险之间存在明确关联。乙醇的促心律失常作用可能是酒精性心肌病患者以及心脏看似正常的患者中某些心律失常和猝死病例的原因。在慢性酗酒者或偶尔大量饮酒者出现任何室上性或室性心律失常的情况下,都应考虑饮酒在引发这些疾病中的潜在作用。在所有情况下,患者管理都包括戒酒和戒酒,但就室性心律失常风险而言,戒断期尤为关键。