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新生儿结核病合并休克、弥散性血管内凝血、噬血细胞综合征及高钙血症:一例报告

Neonatal tuberculosis associated with shock, disseminated intravascular coagulation, hemophagocytic syndrome, and hypercalcemia: a case report.

作者信息

Okascharoen Chusak, Nuntnarumit Pracha, Sirinavin Sayomporn

机构信息

Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Perinatol. 2003 Jan;23(1):79-81. doi: 10.1038/sj.jp.7210848.

DOI:10.1038/sj.jp.7210848
PMID:12556935
Abstract

We report on a female infant with disseminated tuberculosis who presented with clinical sepsis and disseminated intravascular coagulation starting at 14 days of age. Parenteral ofloxacin combined with streptomycin were used because the enteral route was not possible and intravenous isoniazid and rifampicin were not available. Rare complications including infection-associated hemophagocytic syndrome, hypercalcemia, and adrenal insufficiency were detected and successfully managed.

摘要

我们报告了一名患有播散性结核病的女婴,她在14日龄时出现临床败血症和弥散性血管内凝血。由于无法采用肠内给药途径且没有静脉用异烟肼和利福平,因此使用了胃肠外氧氟沙星联合链霉素治疗。检测到包括感染相关噬血细胞综合征、高钙血症和肾上腺功能不全在内的罕见并发症,并成功进行了处理。

相似文献

1
Neonatal tuberculosis associated with shock, disseminated intravascular coagulation, hemophagocytic syndrome, and hypercalcemia: a case report.新生儿结核病合并休克、弥散性血管内凝血、噬血细胞综合征及高钙血症:一例报告
J Perinatol. 2003 Jan;23(1):79-81. doi: 10.1038/sj.jp.7210848.
2
Tuberculosis associated hemophagocytic syndrome complicated with severe bone marrow failure and disseminated intravascular coagulation.结核相关噬血细胞综合征并发严重骨髓衰竭及弥散性血管内凝血。
Nouv Rev Fr Hematol (1978). 1992;34(3):273-6.
3
[Disseminated intravascular coagulation syndrome in sepsis in infants].[婴儿脓毒症中的弥散性血管内凝血综合征]
Vestn Khir Im I I Grek. 1978 Sep;121(9):84-8.
4
[Reactive hemophagocytic syndrome with disseminated intravascular coagulation secondary to acute brucellosis].
Enferm Infecc Microbiol Clin. 1994 Dec;12(10):519-20.
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Spontaneous resolution of hemophagocytic syndrome and disseminated intravascular coagulation associated with parvovirus b19 infection in a previously healthy child.
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Multiple organ infarctions following disseminated intravascular coagulation precipitated by sepsis in a healthy infant: a case report.多发器官梗死继发于健康婴儿脓毒症弥漫性血管内凝血:病例报告。
Kaohsiung J Med Sci. 2010 Dec;26(12):663-8. doi: 10.1016/S1607-551X(10)70101-7.
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Plasma soluble fibrin monomer complex is a useful predictor of disseminated intravascular coagulation in neonatal sepsis.血浆可溶性纤维蛋白单体复合物是新生儿败血症中弥散性血管内凝血的有用预测指标。
Haematologica. 2005 Mar;90(3):419-21.
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[Hemophagocytic syndrome associated with tuberculosis in a patient infected with the human immunodeficiency virus].[一名感染人类免疫缺陷病毒的患者中与结核病相关的噬血细胞综合征]
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[Syndrome of disseminated intravascular coagulation as the principal morphologic manifestation of shock].以弥散性血管内凝血综合征作为休克的主要形态学表现
Arkh Patol. 1983;45(12):13-20.
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[Hemorrhagic necrosis of the marrow in neonatal sepsis complicated by disseminated intravascular coagulation].
Minerva Pediatr. 1979 Jun 30;31(12):975-8.

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Clinical features, treatment outcomes and mortality risk of tuberculosis sepsis in HIV-negative patients: a systematic review and meta-analysis of case reports.HIV 阴性结核病脓毒症患者的临床特征、治疗结局和死亡风险:病例报告的系统评价和荟萃分析。
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Intern Med. 2017;56(12):1591-1596. doi: 10.2169/internalmedicine.56.8025. Epub 2017 Jun 15.
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[Nephrocalcinosis complicating miliary tuberculosis in an infant].[婴儿粟粒性肺结核并发肾钙质沉着症]
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J Perinatol. 2016 Feb;36(2):80-5. doi: 10.1038/jp.2015.99. Epub 2015 Aug 13.
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