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胎儿手术的微创技术。

Minimal access techniques for fetal surgery.

作者信息

Sydorak Roman M, Albanese Craig T

机构信息

The Fetal Treatment Center, Department of Surgery, Division of Pediatric Surgery, University of California, San Francisco, 513 Parnassus Avenue, Room HSW 1601, San Francisco, California 94143, USA.

出版信息

World J Surg. 2003 Jan;27(1):95-102. doi: 10.1007/s00268-002-6743-4.

Abstract

The impetus for the development of minimal access techniques for fetal surgery was the unusual occurrence with open hysterotomy of preterm labor, premature rupture of membranes, and the maternal complications resulting from tocolytic therapy. This strategy involves a constellation of techniques that allow surgical procedures to be performed inside the uterus without a hysterotomy. The unique requirements of this approach necessitated modifications of existing endoscopic techniques, development of novel fetoscopic instruments, and utilization of the expertise of a wide variety of specialists. Technical expertise in the field and a natural evolution of techniques have given rise to innovative repairs previously not envisioned. Severe congenital diaphragmatic hernia, diseases of monochorionic twins, and obstructive uropathy have already been successfully treated using fetoscopic surgical techniques. Fetoscopic correction of many other non-life-threatening anomalies continues to evolve. The future of fetoscopic surgical intervention depends on the continual evolution of novel techniques, the elucidation of the pathophysiology and treatment of other fetal disorders, and a better understanding of treatment of complications of intervention.

摘要

胎儿手术微创技术发展的动力源于开放性子宫切开术引发的早产、胎膜早破以及宫缩抑制剂治疗导致的母体并发症等异常情况。该策略涉及一系列技术,可在不进行子宫切开术的情况下在子宫内实施手术操作。这种方法的独特要求促使对现有内镜技术进行改进,研发新型胎儿镜器械,并利用各类专家的专业知识。该领域的技术专长以及技术的自然演进催生了此前未曾设想过的创新性修复方法。严重先天性膈疝、单绒毛膜双胎疾病以及梗阻性尿路病已通过胎儿镜手术技术成功得到治疗。胎儿镜对许多其他非危及生命的畸形的矫正仍在不断发展。胎儿镜手术干预的未来取决于新技术的持续演进、对其他胎儿疾病病理生理学和治疗方法的阐明,以及对干预并发症治疗的更好理解。

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