Sydorak R M, Nijagal A, Albanese C T
The Fetal Treatment Center, University of California San Francisco, 513 Parnassus Ave., Room HSW 1601, San Francisco, CA 94143-0570, USA.
Yonsei Med J. 2001 Dec;42(6):695-710. doi: 10.3349/ymj.2001.42.6.695.
Fetal endoscopic surgery (FETENDO) involves many techniques that allow surgical procedures to be performed inside the uterus without an hysterotomy. The impetus for developing these minimal access techniques for fetal surgery is the unusual occurrence with an open hysterotomy of preterm labor, premature rupture of membranes, and maternal complications resulting from tocolytic therapy. The unique requirements of this approach necessitated a modification of existing endoscopic techniques, the development of novel fetoscopic instruments, and the inclusion of a wide variety of specialists. Technical expertise in the field and a natural evolution of techniques have given rise to innovative repairs previously not envisioned. Severe congenital diaphragmatic hernia, diseases of monochorionic twins, and obstructive uropathy have already been successfully treated using fetoscopic surgical techniques. Fetoscopic correction of many other non-life threatening anomalies continues to evolve. The future of fetoscopic surgical intervention depends on the continual evolution of novel approaches to disease, the elucidation of the pathophysiology and treatment of other fetal disorders, and a better understanding of treatment of complications of such intervention.
胎儿内镜手术(FETENDO)涉及多种技术,这些技术使得在不进行子宫切开术的情况下就能在子宫内实施手术操作。开发这些用于胎儿手术的微创技术的动力在于,子宫切开术后早产、胎膜早破以及因宫缩抑制剂治疗导致的母体并发症的异常发生率。这种手术方式的独特要求促使人们对现有的内镜技术进行改进,开发新型胎儿镜器械,并纳入各类专家。该领域的技术专长以及技术的自然发展催生了此前未曾设想过的创新性修复方法。严重先天性膈疝、单绒毛膜双胎疾病以及梗阻性尿路病已通过胎儿镜手术技术成功得到治疗。对许多其他非危及生命的畸形进行胎儿镜矫正的技术也在不断发展。胎儿镜手术干预的未来取决于针对疾病的新方法的持续发展、对其他胎儿疾病病理生理学及治疗方法的阐明,以及对这种干预并发症治疗的更深入理解。