Kovacs Gabor T, Breheny Sue A, Dear Melinda J
Monash IVF, Monash University, Richmond, VIC, Australia.
Med J Aust. 2003 Feb 3;178(3):127-9. doi: 10.5694/j.1326-5377.2003.tb05103.x.
To review the choices of couples relinquishing frozen embryos and the outcomes of embryo donation at a major in-vitro fertilisation (IVF) clinic.
Retrospective audit of 11.5 years of data (1991-2002) from the Monash University IVF clinic, Melbourne.
Couples who make decisions regarding the fate of their frozen embryos, and recipient couples taking part in embryo adoption.
Couples' choices with regard to the fate of their frozen embryos, and the outcome of donated embryo treatment cycles.
Of 1246 couples relinquishing frozen embryos, 1116 (89.5%) opted to discard rather than donate their embryos. Sixty-six per cent of donated embryos survived thawing. From donated-embryo transfer to 50 women in 92 cycles, a 17.4% pregnancy rate per transfer cycle was achieved, and 10 women delivered 11 healthy babies at term. At the time of our audit there were 98 couples on the waiting list to adopt embryos.
It is worth considering how couples can be encouraged to donate rather than discard their surplus frozen embryos. An educational program on relevant legal, social and clinical issues may facilitate this.
回顾在一家大型体外受精（IVF）诊所中，放弃冷冻胚胎的夫妇的选择以及胚胎捐赠的结果。
对墨尔本莫纳什大学IVF诊所11.5年（1991 - 2002年）的数据进行回顾性审计。
对其冷冻胚胎的命运做出决定的夫妇，以及参与胚胎收养的接受夫妇。
夫妇对其冷冻胚胎命运的选择，以及捐赠胚胎治疗周期的结果。
在1246对放弃冷冻胚胎的夫妇中，1116对（89.5%）选择丢弃而非捐赠他们的胚胎。66%的捐赠胚胎解冻后存活。在92个周期中向50名女性进行了捐赠胚胎移植，每个移植周期的妊娠率为17.4%，10名女性足月产下11名健康婴儿。在我们审计时，有98对夫妇在等待收养胚胎的名单上。
值得思考如何鼓励夫妇捐赠而非丢弃他们多余的冷冻胚胎。关于相关法律、社会和临床问题的教育项目可能会促进这一点。
