Van Loon A Jeanne M, Tijhuis Marja, Picavet H Susan J, Surtees Paul G, Ormel Johan
National Institute of Public Health and the Environment, Bilthoven, The Netherlands.
Ann Epidemiol. 2003 Feb;13(2):105-10. doi: 10.1016/s1047-2797(02)00257-0.
Differences in respondent characteristics may lead to bias in prevalence estimates and bias in associations. Both forms of non-response bias are investigated in a study on psychosocial factors and cancer risk, which is a sub-study of a large-scale monitoring survey in the Netherlands.
Respondents of a cross-sectional monitoring project (MORGEN; N = 22,769) were also asked to participate in a prospective study on psychosocial factors and cancer risk (HLEQ; N = 12,097). To investigate diverse aspects of non-response in the HLEQ on prevalence estimates and associations are studied, based on information gathered in the MORGEN-project.
A response percentage of 45% was obtained in the MORGEN-project. Response rates were found to be lower among men and younger people. The HLEQ showed a response percentage of 56%, and respondents reported higher socioeconomic status, better subjective health and healthier lifestyle behaviors than non-respondents. However, associations between smoking status and either socioeconomic status or subjective health based on respondents only were not statistically different from those based on the entire MORGEN-population.
Non-response leads to bias in prevalence estimates of current smoking, current alcohol intake, and low physical activity or poor subjective health. However, non-response did not cause bias in the examined associations.
应答者特征的差异可能导致患病率估计偏差和关联偏差。在一项关于心理社会因素与癌症风险的研究中,对这两种无应答偏差形式进行了调查,该研究是荷兰一项大规模监测调查的子研究。
一项横断面监测项目(MORGEN;N = 22,769)的应答者也被要求参与一项关于心理社会因素与癌症风险的前瞻性研究(HLEQ;N = 12,097)。基于MORGEN项目收集的信息,研究HLEQ中无应答在患病率估计和关联方面的不同情况。
MORGEN项目的应答率为45%。发现男性和年轻人的应答率较低。HLEQ的应答率为56%,与未应答者相比,应答者报告的社会经济地位更高、主观健康状况更好且生活方式行为更健康。然而,仅基于应答者的吸烟状况与社会经济地位或主观健康之间的关联与基于整个MORGEN人群的关联在统计学上并无差异。
无应答导致当前吸烟、当前饮酒以及低体力活动或主观健康状况不佳的患病率估计出现偏差。然而,无应答并未在所检查的关联中造成偏差。