Mostafa A A, Zayed A B
Research Institute of Medical Entomology, Dokki, Giza, Egypt.
J Egypt Soc Parasitol. 1999;29(1):193-201.
Susceptibility tests for house fly Musca domestica collected from Gamasa City and laboratory bred one were carried out. The data suggested that the levels of resistance in Gamasa population against malathion, diazinon, diamethoate (organophosphorus compounds) and permethrin (pyrethroid one) were developed while deltamethrin and cypermethrin were still effective. The highest homogenity response was for malathion followed by dimethoate, deltamethrin and cypermethrin. On the other hand, the highest homogenity response in laboratory population was that of cypermethrin and deltamethrin followed by malathion, dimethoate, permethrin and then diazinon. The EST activity was higher in laboratory population (three heavy bands), than Gamasa one (two faint bands), while the activity of LDH and G-6PDH were higher in Gamasa population than in laboratory one. The ADH activity was the same in both populations. This means that EST was not the main detoxifying target in Musca domestica.
对从加马萨市采集的家蝇以及实验室培育的家蝇进行了药敏试验。数据表明,加马萨种群对马拉硫磷、二嗪农、乐果(有机磷化合物)和氯菊酯(拟除虫菊酯类)产生了抗性,而溴氰菊酯和氯氰菊酯仍然有效。对马拉硫磷的同质性反应最高,其次是乐果、溴氰菊酯和氯氰菊酯。另一方面,实验室种群中同质性反应最高的是氯氰菊酯和溴氰菊酯,其次是马拉硫磷、乐果、氯菊酯,然后是二嗪农。酯酶(EST)活性在实验室种群中(三条重带)高于加马萨种群(两条淡带),而乳酸脱氢酶(LDH)和葡萄糖-6-磷酸脱氢酶(G-6PDH)的活性在加马萨种群中高于实验室种群。乙醇脱氢酶(ADH)活性在两个种群中相同。这意味着酯酶不是家蝇的主要解毒靶点。